Olarigen 150mg (Generic Lynparza)

Olarigen 150 mg represents a precision oncology treatment manufactured by General Pharmaceuticals Ltd. It contains Olaparib, a potent inhibitor of PARP enzymes (PARP1, PARP2, and PARP3). This medication utilizes the concept of “synthetic lethality” to target tumor cells that have a deficiency in their Homologous Recombination Repair (HRR) pathway, such as those with BRCA1 or BRCA2 mutations.

Manufacturing Quality

Olarigen is produced in a specialized oncology facility designed to meet rigorous international standards. General Pharmaceuticals Ltd. emphasizes adherence to cGMP (Current Good Manufacturing Practice) guidelines to ensure the stability and potency of the active ingredient.

Who Is This Medication For?

Olarigen is indicated for adult patients with:

• Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cancer: Used to maintain a response after chemotherapy.

• Metastatic Breast Cancer: Specifically for patients with inherited BRCA mutations who have previously received chemotherapy. 

• Prostate and Pancreatic Cancers: Targeted treatment for specific genetic profiles as determined by your oncologist. 

Dosage and Administration of Olarigen

The general dosage information of olarigen is 15 mg twice a day for adult patients for up to 1 year. As it is general information it may change according to the doctor’s prescription and the patient’s medical condition. The dosage might be changed if the patient faces any severe problems while taking olarigen.

It is an oral medication. Patients can swallow it or make a suspension of it and drink it. It is administrable with or without food which is preferable to the patient or suggested by a doctor.

For below 12 years patient, they must follow doctors’ suggestions.

Patient Management Tips

• Managing Nausea: Nausea is common when starting therapy. Eating small, frequent, bland meals (like toast or crackers) and avoiding greasy or spicy foods can help.   

• Fatigue: You may feel unusually tired. Prioritize rest and try light activities like short walks to maintain energy levels. 

• Blood Work: It is essential to check your Complete Blood Count (CBC) monthly for the first year of treatment to detect any drop in hemoglobin or white blood cells. 

Storage and Handling

Store Olarigen below 30°C in a dry place. Do not expose the medication to extreme heat or humidity, which is common in the local climate. Keep out of reach of children. 

Market Information

When evaluating treatment options, patients often compare the generic Olaparib 150 mg price in Bangladesh to understand the differences between available brands. Olarigen 150 mg is frequently listed at a premium price point. This price reflects the product’s positioning and manufacturing attributes. Patients should discuss with their healthcare provider whether this specific formulation is suitable for their treatment plan and budget.

Here are Some FAQs about Olarigen

Q: How does Olarigen 150 mg work against cancer?

A: Olarigen works by blocking a protein called PARP in your cells. PARP helps repair damaged DNA. Cancer cells with specific mutations (like BRCA) rely heavily on PARP to survive. When Olarigen blocks this protein, the cancer cells cannot repair their DNA and die, while healthy cells are generally able to use other repair methods to survive.

Q: Why is the price of Olarigen different from other brands?

A: Patients researching the generic Lynparza 150 mg price in Bangladesh often notice that Olarigen is positioned at a premium price point. This pricing often reflects the manufacturer’s investment in specialized oncology facilities that comply with rigorous international standards (such as EU-GMP and TGA), ensuring a high level of quality assurance for the product.

Q: How should I store Olarigen tablets at home?

A: It is critical to store Olarigen below 30°C in a dry place. In the Bangladeshi climate, it is advisable to keep the medicine away from direct sunlight, windows, or humid areas like bathrooms. If your home gets very hot, consider storing the bottle in a cool, dark cupboard or a dedicated medication cooler.

Q: What monitoring is required while taking this medication?

A: Your oncologist will require you to have a Complete Blood Count (CBC) test before starting treatment and monthly for at least the first year. This is to monitor for side effects like anemia (low red blood cells) or neutropenia (low white blood cells). Renal function (kidney tests) will also be checked periodically.

Q: Is Olarigen the same as the 50 mg capsules?

A: No. Olarigen 150 mg is a tablet formulation. It is not interchangeable with the older 50 mg capsules on a milligram-to-milligram basis due to differences in how the body absorbs them. You should strictly follow the prescription provided by your doctor and not switch between capsules and tablets without medical guidance.

Disclaimer: These product pages are for informational purposes only and do not constitute medical advice. Treatment decisions should always be made in consultation with a qualified oncologist.