Olanib 150 mg (Generic Olaparib) Tablets

Olanib 150 mg is a targeted therapy medication belonging to a class of drugs known as PARP (Poly ADP-ribose Polymerase) inhibitors. It is designed to treat specific types of cancers—primarily ovarian, breast, prostate, and pancreatic cancers—that harbor mutations in the BRCA genes. By inhibiting the PARP enzyme, Olanib prevents cancer cells from repairing their damaged DNA, leading to cell death while largely sparing normal, healthy cells.

Clinical Indications

Your oncologist may prescribe Olanib for the following conditions:

Ovarian Cancer: As maintenance treatment after responding to platinum-based chemotherapy, particularly for patients with BRCA mutations or genomic instability.
Breast Cancer: For patients with germline BRCA-mutated, HER2-negative metastatic breast cancer who have been treated with chemotherapy.
Prostate Cancer: For metastatic castration-resistant prostate cancer (mCRPC) with specific gene mutations (BRCA1, BRCA2, ATM).
Pancreatic Cancer: As maintenance treatment for germline BRCA-mutated metastatic pancreatic cancer.

Dosing and Administration

Standard Dose: The typical recommended dose is 300 mg (two 150 mg tablets) taken twice daily, for a total of 600 mg per day.
How to Take: Swallow the tablets whole. Do not chew, crush, or dissolve them. They can be taken with or without food.
Missed Dose: If you miss a dose, take your next dose at the scheduled time. Do not take an extra dose to make up for the missed one.

Understanding Treatment Costs

For patients requiring long-term maintenance therapy, financial planning is a critical aspect of care. The generic Olaparib 150 mg price in Bangladesh varies significantly depending on the manufacturer and pack size. Olanib 150 mg is generally positioned as a cost-effective option within the local market, with prices for a monthly supply (120 tablets) typically ranging between 12,000 BDT and 48,000 BDT, subject to pharmacy availability and specific batch imports. Patients are advised to consult with authorized hospital pharmacies to verify the current MRP.

Important Safety Information

Dietary Restrictions: Avoid grapefruit and Seville oranges (often found in marmalade) while taking this medication, as they can increase the level of the drug in your blood to dangerous levels,.
Common Side Effects: Patients may experience nausea, fatigue (tiredness), anemia (low red blood cell count), or vomiting. Your doctor may prescribe anti-nausea medication to help manage these symptoms.
Monitoring: Regular blood tests are required to monitor your blood cell counts and kidney function during treatment.

Storage

Store Olanib tablets in their original bottle below 30°C. Keep the container tightly closed to protect from moisture and light.

Frequently Asked Questions

Q: What is the recommended dosage for Olanib 150 mg?

A: The standard dosage for most patients is 300 mg taken twice daily. This typically means taking two 150 mg tablets in the morning and two 150 mg tablets in the evening, for a total of four tablets (600 mg) per day. However, your oncologist may adjust this dose based on your blood test results or side effects.

Q: How does the generic Olaparib 150 mg price in Bangladesh compare for this brand?

A: Olanib 150 mg is widely recognized as one of the most accessible options in the local market. While the generic Olaparib 150 mg price in Bangladesh can fluctuate based on distribution channels, Olanib is generally priced between 12,000 BDT and 48,000 BDT per box, depending on whether you purchase a trial pack (30 tablets) or a full month’s supply (120 tablets). This pricing structure is designed to support long-term maintenance therapy.

Q: Can I take Olanib with food?

A: Yes, Olanib tablets can be taken with or without food. However, if you experience nausea (a common side effect), taking the medication with a light, bland meal may help settle your stomach.

Q: What should I do if I miss a dose?

A: If you miss a scheduled dose, you should skip that dose and take your next dose at the regular time. Do not take an extra dose or double up to make up for the missed one.

Q: Are there any specific foods I need to avoid?

A: Yes. You must avoid consuming grapefruit and Seville oranges (often used in marmalade) while on this treatment. These fruits contain compounds that interfere with how your body processes the drug, potentially leading to harmful levels in your bloodstream.