Levanix4/10mg-Lenvatinib

Name: Levanix4/10mg-Lenvatinib
Brand: Meds For Cancer
SKU: 2207
Availability: InStock
Rating: 5 (1 reviews)

Description

Levanix4/10mg-Lenvatinib is a TKI used to treat various cancers, including DTC, HCC, RCC, and endometrial cancer when combined with pembrolizumab.

Description and Indication for using Levanix4/10mg-Lenvatinib:

Levanix4/10mg-Lenvatinib is a type of medication known as a multiple receptor tyrosine kinase inhibitor (TKI). It is commonly prescribed to treat several types of cancer, including radioactive iodine-refractory differentiated thyroid cancer (DTC), unresectable hepatocellular carcinoma (HCC), advanced renal cell carcinoma (RCC), and advanced endometrial cancer when taken in conjunction with pembrolizumab. If you are interested in learning more about this medication, its uses, and potential side effects, we can provide you with more information. [1]

Mechanism of Action:

Lenvatinib is a TKI used to treat various cancers, including DTC, HCC, RCC, and endometrial cancer. It works by blocking tyrosine kinases, which are involved in cell growth, division, angiogenesis, and survival. By blocking these enzymes, lenvatinib can slow or stop cancer cell growth and promote their death, reducing the risk of side effects and promoting overall health.

Specifically, lenvatinib inhibits the following tyrosine kinases:

Vascular endothelial growth factor receptors (VEGFR1, VEGFR2, and VEGFR3)
Fibroblast growth factor receptors (FGFR1, FGFR2, FGFR3, and FGFR4)
Platelet-derived growth factor receptor alpha (PDGFRα)
c-Kit
RET proto-oncogene

Tyrosine kinases play a crucial role in tumor growth and progression. Blocking their activity can slow or stop cancer cell growth. Lenvatinib also has anti-angiogenic effects, blocking the formation of new blood vessels essential for tumor growth and metastasis. [2]

Side Effects of using Levanix4/10mg-Lenvatinib:

Lenvatinib can cause diarrhea, fatigue, hypertension, proteinuria, decreased appetite, nausea, stomatitis, and dysphonia. Other side effects include weight loss, rash, dry mouth, hair loss, muscle and joint pain, headache, constipation, vomiting, cough, shortness of breath, dizziness, fainting, liver, kidney, bleeding, heart, and allergic reactions. It is crucial to inform your doctor about any serious side effects to adjust your dose or prescribe additional medications. [3]

Lenvatinib and pembrolizumab:

Lenvatinib and pembrolizumab are two cancer drugs used in combination to treat advanced endometrial cancer. Lenvatinib is a tyrosine kinase inhibitor (TKI) that slows down cancer cell growth and promotes their death. Pembrolizumab is a programmed cell death protein 1 (PD-1) inhibitor that helps T cells recognize and attack cancer cells. The combination is effective, with patients receiving lenvatinib and pembrolizumab having longer overall and progression-free survival compared to chemotherapy alone. However, side effects like diarrhea, fatigue, hypertension, and nausea can occur.

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How effective is Lenvatinib?

Lenvatinib has been shown to improve overall and progression-free survival in patients with certain cancers, such as HCC and RCC. However, it can cause side effects like diarrhea, fatigue, hypertension, proteinuria, decreased appetite, nausea, stomatitis, and dysphonia. Patients should inform their doctors if they experience any serious side effects to adjust their dose or prescribe additional medications.