Rutinib Cream (Ruxolitinib INN 1.5%)

Rutinib Cream is a topical Janus Kinase (JAK) inhibitor designed to treat non-segmental vitiligo and mild-to-moderate atopic dermatitis (eczema). It contains 15 mg (1.5%) of Ruxolitinib INN Phosphate per gram.

How does Rutinib Cream Work?

Rutinib cream works by targeting the immune response that causes skin conditions:

• For Vitiligo: In vitiligo, the body’s immune system attacks melanocytes (the cells that produce skin color). Rutinib blocks the JAK1 and JAK2 enzymes involved in this attack, allowing the skin to recover and potentially allowing pigmentation to return.
• For Eczema: It reduces the overactive immune signals that cause inflammation, redness, and severe itching.

Why Rutinib Cream is used?

This medication is indicated for adults and children (12 years and older) for:

1. Repigmentation in non-segmental vitiligo.

2. Management of mild to moderate atopic dermatitis.

How to apply Rutinib Cream ointment?

• Wash your hands with soap.
• Take a thin layer of the ruxolitinib, then apply it on the affected skin area.
• Take your dermatologist advice before taking this ointment.
• It doesn’t work similarly for every patient, so don’t be impatient while using.
• Results may take time. If you experience side effects consult your dermatologist immediately.

What are the common side effects?

Here are some common side effects of this topical Janus Kinase Inhibitor.

• Increase in eosinophil count ( a type of white blood cell)
• Increase of the irritation in the skin
• It may also cause a skin rash if it does not suit the patient

Additional side effects may occur depending on skin type and severity of the condition, always consult a doctor before use.

Precautions and Warnings

• Serious Infections: With the use of Rutinib cream, patients presenting an active, serious infection should abstain from its usage. This includes localized infections. If a patient develops a serious infection while using Rutinib, it should be interrupted until control over the infection is achieved. The risks and benefits of treatment with Rutinib should be well weighed before starting therapy for any patient having a chronic or recurrent infection. Patients should be under keen observation for any signs and symptoms of infections during and even after treatment with Rutinib.
• Mortality: In patients with rheumatoid arthritis who are at least 50 years old and have one cardiovascular risk factor, when comparing an oral JAK inhibitor to treatment with a tumor necrosis factor (TNF) blocker, a greater incidence of all-cause mortality that included sudden cardiovascular deaths was noted with the JAK inhibitor.
• Non-melanoma skin cancer: Basal cell and squamous cell carcinoma are part of non-melanoma skin cancers which may take place in patients under treatment with Rutinib. Regular skin checks should be done during the time of treatment with Rutinib. Sun exposure and UV light should be limited by wearing protective clothing together with broad-spectrum sunscreen.
• Major Adverse Cardiovascular Events (MACE): Patients who are current or former smokers have an additionally increased risk of major adverse cardiovascular events. In patients who have a myocardial infarction or stroke, discontinue Rutinib.

Rutinib Cream price in the UK

A 30gm tube of Rutinib Cream is typically available for approximately £100 GBP for UK delivery. Final pricing may fluctuate based on international shipping rates, customs duties, and distributor policies. As a generic Ruxolitinib formulation manufactured by Drug International Ltd, it is often sourced via personal import. Patients should verify current pricing and availability with their specific supplier.

Frequently Asked Questions (FAQs)

Is Rutinib Cream safe for long-term use?

No, it is a short term non-continious treatment option for vitiligo and atopic dermatitis. It should be prescribed by a dermatologist and long term treatment should be discussed with health care professionals.

How long does Rutinib Cream take to show results?

The effectiveness of this medication varies person to person. In some cases it takes 8-12 weeks for some patients to work. On the other hand, others patients may need long term treatment under health care professional consultation. Always follow your doctor’s advice for the best results.

Disclaimer: Do not use the above information for medical uses. It is only for general uses and to understand the buying process online. We do not recommend you to buy this medication without your dermatologist’s permission or a valid prescription.