What is Rutinib Cream?
Rutinib cream 1.5% (Ruxolitinib) is a topical janus kinase inhibitor, used to treat atopic dermatitis (eczema) and vitiligo. Eczema causes red, irritated, and itchy skin. Vitiligo is known as skin depegmentation or loss of the melanin hormone. It works by increasing the number of melanin in the skin and remove depegmentation.
What is the Composition of Rutinib cream?
Each gram of Rutinib Cream contains 15 mg (1.5%) of Ruxolitinib INN Phosphate. Each tube contains 30 gm ointment for the external use only.
What is the therapeutic class of this topical vitiligo treatment cream?
This vitiligo treatment is a Janus Kinase (JAK) Inhibitor.
How does it Work?
- It works by blocking JAK1 and JAk2 enzymes. These enzymes are involved in inflammation of the skin, itch and irritation.
- When the body’s immune system starts working against the melanin hormone considered a threat, the skin loses its color.
- For this reason, vitiligo is also known as an autoimmune disease. Here, this inhibitor helps to improve the skin condition.
Why Rutinib Cream is used?
It is used in adult or children of 12 years age to treat
- Non-segmental vitiligo.
- Mild to moderate atopic dermatitis.
How to apply this ointment?
- Wash your hands with soap.
- Take a thin layer of the ruxolitinib, then apply it on the affected skin area.
- Take your dermatologist advice before taking this ointment.
- It doesn’t work similarly for every patient, so don’t be impatient while using.
- Results may take time. If you experience side effects consult your dermatologist immediately.
What are the common side effects?
Here are some common side effects of this topical Janus Kinase Inhibitor.
- Increase in eosinophil count ( a type of white blood cell)
- Increase of the irritation in the skin
- It may also cause a skin rash if it does not suit the patient
Additional side effects may occur depending on skin type and severity of the condition, always consult a doctor before use.
Rutinib Cream 1.5 for Alopecia Areata
Yet it is not indicated to treat alopecia areata or hair loss. A phase-II study on alopecia areata found no significant improvement in hair re-growth. However, if your doctor prescribes oral Rutinib for alopecia areata you may take it under medical supervison. Since alopecia areata is an auto immune disorder, treatment may vary. Do not take this medication without your doctor’s approval. As it may lead to serious side effects.
Precautions and Warnings
Serious Infections: With the use of Rutinib, patients presenting an active, serious infection should abstain from its usage. This includes localized infections. If a patient develops a serious infection while using Rutinib, it should be interrupted until control over the infection is achieved. The risks and benefits of treatment with Rutinib should be well weighed before starting therapy for any patient having a chronic or recurrent infection. Patients should be under keen observation for any signs and symptoms of infections during and even after treatment with Rutinib.
Mortality: In patients with rheumatoid arthritis who are at least 50 years old and have one cardiovascular risk factor, when comparing an oral JAK inhibitor to treatment with a tumor necrosis factor (TNF) blocker, a greater incidence of all-cause mortality that included sudden cardiovascular deaths was noted with the JAK inhibitor.
Non-melanoma skin cancer: Basal cell and squamous cell carcinoma are part of non-melanoma skin cancers which may take place in patients under treatment with Rutinib. Regular skin checks should be done during the time of treatment with Rutinib. Sun exposure and UV light should be limited by wearing protective clothing together with broad-spectrum sunscreen.
Major Adverse Cardiovascular Events (MACE): Patients who are current or former smokers have an additionally increased risk of major adverse cardiovascular events. In patients who have a myocardial infarction or stroke, discontinue Rutinib.
What is the price of Rutinib Cream?
In Bangladesh, the cost is around 8,000 TK, while in India it is approximately 7,000 INR. Prices may vary, so patients are advised to check with the supplier.
Accessing Rutinib Cream Through Verified Pharmacies
This prescription ointment can be purchased through verified online pharmacies such as Meds for Cancer. We accept multiple secure payment methods and provide international shipping.
Frequently Asked Questions (FAQs)
Is it safe for long-term use?
No, it is a short term non-continious treatment option for vitiligo and atopic dermatitis. It should be prescribed by a dermatologist and long term treatment should be discussed with health care professionals.
How long does it take to show results?
The effectiveness of this medication varies person to person. In some cases it takes 8-12 weeks for some patients to work. On the other hand, others patients may need long term treatment under health care professional consultation. Always follow your doctor’s advice for the best results.
Learn more about vitiligo on our blog, including topics like , Sunscreen for vitiligo, vitiligo overview
N:B For more information, look at Opzelura.com
Disclaimer: Do not use the above information for medical uses. It is only for general uses and to understand the buying process online. We do not recommend you to buy this medication without your dermatologist’s permission or a valid prescription.
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