Package Insert for Rizonib-250mg-Crizotinib
Rizonib-250mg-Crizotinib is a third-generation inhibitor of EGFR (epidermal growth factor receptor ) tyrosine kinase that hinders the activity of mutated EGFR, thereby slowing down or stopping the growth of cancer cells. It is particularly effective against the T790M mutation, which is a common resistance mutation observed in patients treated with other EGFR TKIs. Rizonib-250mg is highly targeted and is known to impact cancer cells more than healthy ones, thus reducing the risk of side effects. (1)
Rizonib-250mg-Crizotinib is a medication used to treat two types of metastatic non-small cell lung cancer (NSCLC) that have specific genetic mutations. It is only prescribed to patients whose tumors test positive for either the anaplastic lymphoma kinase (ALK) or ROS1 proteins, as detected by an FDA-approved test.
Rizonib-250mg works by inhibiting the activity of these proteins, which play a crucial role in the growth and survival of cancer cells. By blocking their activity, Rizonib-250mg can help slow or stop the growth of cancer cells. (2)
Mechanism of Action of Rizonib-250mg-Crizotinib
Rizonib-250mg-Crizotinib is a type of medication known as a tyrosine kinase inhibitor (TKI). It works by blocking the activity of two proteins, anaplastic lymphoma kinase (ALK) and ROS1, which play a crucial role in the growth and survival of cancer cells. By inhibiting the activity of these proteins, Rizonib-250mg helps to slow down or even halt the growth of cancer cells.
The way Rizonib-250mg works is by binding to the ATP-binding site of ALK and ROS1 proteins, thus preventing them from binding to ATP. ATP is a molecule that these proteins need to function. When the proteins are unable to bind to ATP, they are unable to phosphorylate other proteins, which is essential for them to signal the cell to grow and divide.
As a result, cancer cells stop growing and dividing. Over time, the tumor shrinks, and the cancer may go into remission. (3)
Dosage and Administration for Rizonib-250mg-Crizotinib
Rizonib-250mg-Crizotinib is a medication recommended for adult patients with metastatic non-small cell lung cancer (NSCLC) who have either ALK-positive or ROS1-positive tumors.
- The medication should be taken orally, with or without food, twice a day, with a 12-hour interval between doses.
- It is important to take the medication at the same time each day to ensure a constant drug amount in the body.
- If you miss a dose, take it as soon as you remember, skip the missed dose if it is almost time for your next scheduled dose, and follow your regular dosing schedule.
- Dosage adjustments may be required if you experience side effects or if you are taking other medications that can interact with rizonib.
- Before starting rizonib, it is important to inform your doctor about all the medications you are taking, including over-the-counter medications, herbal supplements, and vitamins.
- To take rizonib, swallow the capsules whole with water or mix them with applesauce, pudding, or yogurt, and take on an empty stomach. (4)
Side Effects of Rizonib-250mg-Crizotinib
The most common side effects of Rizonib-250mg are:
- Abdominal pain
- Vision problems
Less common side effects of rizonib include:
- Liver damage
- Kidney damage
- Lung damage
- Heart problems
- Allergic reactions (4)
Cost and Medication Access
Anti-cancer medicines are very expensive almost 90% of cancer patients can not afford these medicine. Some of them get access of these medicines by their insurance but insurance cost is also high for these medicines. That’s why patients do not get proper treatment. Meds for Cancer make these medicine affordable for those patients who cannot buy these expensive medicine or they are not covered by health insurance. We provide the best quality medicine at best price at every corner of the world. To know the Price of these medicine get in touch with us. Contacting us is very easy you can use this number +8801304498958 to contact through WhatsApp and Wechat.
1. What is Rizonib-250mg-Crizotinib?
Rizonib 250mg, also known as Crizotinib, is a medication prescribed for the treatment of specific types of cancer, including non-small cell lung cancer with ALK fusion or ROS1 rearrangement
1. How does Rizonib-250mg-Crizotinib work?
2. Rizonib 250mg (Crizotinib) belongs to a class of drugs called tyrosine kinase inhibitors. It works by inhibiting the activity of abnormal proteins known as ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1), which are involved in the growth and spread of cancer cells.
3. How is Rizonib-250mg-Crizotinib administered?
4. Rizonib 250mg (Crizotinib) is typically taken orally in the form of capsules. The dosage and treatment duration will be determined by your healthcare provider based on your specific condition and response to the medication. It is important to follow the prescribed dosing instructions carefully.
5. What are the common side effects of Rizonib-250mg-Crizotinib?
6. Some common side effects of Rizonib 250mg (Crizotinib) may include nausea, diarrhea, vomiting, constipation, fatigue, edema (swelling), abnormal liver function tests, and changes in vision. It is important to inform your doctor about any side effects you experience.
7. Are there any precautions or warnings associated with Rizonib 250mg (Crizotinib)?
Rizonib 250mg (Crizotinib) may interact with other medications, so it is important to disclose all medications you are taking to your doctor. It may also cause lung problems or irregular heartbeat, so regular medical check-ups and monitoring are necessary during treatment.
8. Can Rizonib-250mg-Crizotinib be used during pregnancy or while breastfeeding?
Rizonib 250mg (Crizotinib) may cause harm to a developing fetus, and its safety during pregnancy has not been established. It is not recommended to use this medication if you are pregnant or planning to become pregnant. It is also advised to avoid breastfeeding while taking Rizonib 250mg (Crizotinib).
9. How effective is Rizonib-250mg-Crizotinib in treating cancer?
Rizonib 250mg (Crizotinib) has shown significant effectiveness in treating specific types of cancer, particularly non-small cell lung cancer with ALK fusion or ROS1 rearrangement. However, the response to the medication may vary among individuals. Your doctor will assess the potential benefits and risks based on your specific condition.
10. Can Rizonib 250mg (Crizotinib) be used for other types of cancer?
Rizonib 250mg (Crizotinib) is primarily indicated for non-small cell lung cancer with ALK fusion or ROS1 rearrangement. Its effectiveness in other types of cancer may vary, and the decision to use it for other conditions should be made by your healthcare provider based on individual considerations.
- what are the other medicines being used to treat non-small cell lung cancer? Tagrix-80mg, Osimert, and osicent are used to treat non-small cell lung cancer.