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Product Name: Cabozanix

Generic Name:  Cabozantinib

Formation: Tablet

Available Pack Size: 90’s plot and 30’s plot

Strength: 20mg and 60mg

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Cabozanix-20mg-Cabozantinib| Package Insert


Cabozanix-20mg-Cabozantinib is a drug, used to treat specific cancers. It is an oral, small-molecule tyrosine kinase inhibitor that targets MET, VEGFR (vascular endothelial growth factor receptor), and RET, in addition to other RTKs. Cabozanix-20mg assists in preventing tumor growth, angiogenesis (the growth of new blood vessels to support the tumor), and metastasis (the spread of cancer to other parts of the body) by inhibiting these kinases.

For patients who have previously received other systemic therapies, the drug Cabozanix-20mg is approved for the treatment of several cancers, including advanced renal cell carcinoma (kidney cancer) and hepatocellular carcinoma (liver cancer). In some cases of medullary thyroid cancer, it may also be applied.

Patients must discuss the potential advantages and disadvantages of Cabozanix-20mg with their oncologist or healthcare provider.


Cabozanix-20mg-Cabozantinib is a multi-indication cancer treatment that is indicated for the treatment of the following:

  • Nivolumab alone or in combination with single agent for the first-line treatment of advanced renal cell carcinoma (RCC).
  • Patients with hepatocellular carcinoma (HCC) who have received sorafenib treatment in the past.
  • Differentiated thyroid cancer (DTC) that is locally advanced or metastatic, has progressed after receiving prior VEGFR-targeted therapy and is radioactive iodine-resistant or ineligible for radioactive iodine therapy.

Mechanism of Action

Cabozanix-20mg-Cabozantinib is multi-kinase inhibitor that inhibits the activity of specific proteins known as receptor tyrosine kinases (RTKs) toorder to produce its desired effects. RTKs play role in several cellular functions, such as cell division, growth, and survival. Overactive RTKs can promote the growth and metastasis of cancer cells.

Cabozanix-20mg specifically inhibits the activity of the following RTKs:

  • MET
  • VEGFR1-3
  • AXL
  • RET
  • ROS1
  • TYRO3
  • MER
  • KIT
  • TRKB
  • FLT-3
  • TIE-2

By blocking the activity of these RTKs, Cabozanix-20mg can slow down or stop cancer cell growth and metastasis. It can also help shrink tumors and improve survival rates.

In addition to its direct effects on tumor cells, Cabozanix-20mg can also affect the tumor microenvironment. The tumor microenvironment is the tissue and cells that surround a tumor. It can play a role in tumor growth and metastasis.

It is important for patients to closely monitor their symptoms and report any concerning side effects to their healthcare provider. Regular check-ups and blood tests may be necessary to monitor organ function while taking Cabozanix-20mg. In some cases, the benefits of the treatment may outweigh the potential risks, especially for patients with advanced or metastatic cancer. However, it is crucial for healthcare providers to carefully weigh the potential benefits against the risks before prescribing Cabozanix-20mg to a patient.

Dosage & Administration

Cabozanix-20mg-Cabozantinib dosage and administration depend on the cancer type and individual medical condition. Doctors determine the best dosage and schedule. For advanced renal cell carcinoma, 60 mg daily is recommended, while for hepatocellular carcinoma and DTC, 40 mg daily is recommended. Doctors may adjust dosage based on response and side effects.

Here are some general guidelines for taking Cabozanix-20mg:

  • Take Cabozanix-20mg at the same time each day.
  • You can take Cabozanix-20mg-Cabozantinib with or without food.
  • If you miss a dose of cabozantinib, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose at the usual time. Do not take a double dose to make up for a missed dose.
  • Swallow cabozantinib tablets whole with water. Do not chew, crush, or break the tablets.
  • Avoid taking cabozantinib with grapefruit or grapefruit juice, as this can increase the levels of cabozantinib in your blood and increase the risk of side effects.
  • Store cabozantinib tablets at room temperature, away from moisture and heat.

Side Effects of Cabozanix-20mg-Cabozantinib

Cabozanix-20mg-Cabozantinib is a drug that can have several negative side effects, such as diarrhea, nausea, vomiting, fatigue, high blood pressure, hand-foot syndrome, decreased appetite, hair loss, dry skin, mouth sores, constipation, headache, muscle pain, joint pain, difficulty sleeping, and rash. Liver damage, kidney damage, bleeding, blood clots, heart problems, lung problems, infection, seizures, and stroke are less frequent but more severe side effects. Consult your doctor for advice on how to deal with any of these side effects or how to change the dosage if you experience any of them.

Brand Name

The brand names of cabozantinib are:

  • Cometriq
  • Cabometyx

Cometriq is used to treat medullary thyroid cancer. Cabometyx is used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and locally advanced or metastatic differentiated thyroid cancer.

Price of Cabozanix-20mg-Cabozantinib

The price of cabozantinib can vary depending on the brand name, dosage, and pharmacy where you purchase it. However, it is generally a very expensive medication.

According to GoodRx, the average cost of a 30-day supply of Cabometyx 40 mg tablets is $52,576.54. The price can range from $24,943.93 to $65,157.26, depending on the pharmacy.

The generic version of this medicine is Cabozanix-20mg which is much less from the brand name medicine and effective as the brand one.

Cabozanix-20mg-Cabozantinib Success Rate:

After approval by FDA Cabozantinib has shown an emerge success in renal cell carcinoma treatment. Even in the field study and clinical trial it has proved to be a best treatment option for renal cell carcinoma.

Cabozanix-20mg-Cabozantinib Life Expectancy

Cabozantinib’s life expectancy varies based on the cancer type and individual condition. However, it has been shown to improve survival rates in various cancers. In a clinical trial, it increased median overall survival in patients with advanced renal cell carcinoma, extended it in those with hepatocellular carcinoma who had previously received sorafenib, and extended it in patients with locally advanced or metastatic differentiated thyroid cancer who had progressed after prior VEGFR-targeted therapy.

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