Azarest-300mg(Azacitidine) Package Insert

What Is Azacitidine?

Azarest-300mg, an oral chemotherapy drug, is available in tablet and injection form (Azarest-100 mg injection). Tablet should not be used instead of injection. It works by slowing or stopping the cancer cells in the patient’s body.

Doctors use this drug to treat a specific type of cancer, Acute Myeloid Leukemia (AML). AML is a disease of blood and a subtype of leukemia. Whoever wants to use this medication must get a doctor’s or health care professional’s permission.

Indications For Using Azarest-300mg

azarest-300mg is a blood disease treating medication. Doctors use this medication to treat the following types of disease

• Myelodysplastic syndromes (MDS): a group of bone marrow disorders leading to insufficient healthy blood cell production.
• Acute myeloid leukemia (AML): in adults who achieved remission after initial chemotherapy but can’t undergo further intensive treatment.
• Juvenile myelomonocytic leukemia (JMML): in newly diagnosed patients aged 1 month and older.

The patients who have reached complete remission (CR) and complete remission with blood count recovery (CRi). In both cases doctors use this medication after initial intensive treatment. Where patients are unable to take more intensive treatment

Azarest-300mg(Azacitidine) Mechanism of Action

As it is a chemotherapy drug, it slows or stops growing cancer cells. It helps reduce blood supply to the cells and stops the potential growth of the cells. By doing that, it helps patients in recovering from cancer.

Because of is an oral medication, it starts working when a patient swallows it. This medication targets specific cancer cells called acute myeloid leukemia.

Dosage and Administration for Azarest-300mg

300 mg is a common dose for azarest. It has to be taken orally by adult patients as described in the prescription. Patients can take this medication with or without food, as directed by their healthcare professional. If you are a patient with AML, you must remember the below key points before taking this medication:

• Do not take this medication without a proper guideline
• Maintain your doses regularly
• Do not stop taking until your doctor forbids you
• If you face any side effects, severe or mild, inform your doctor fast
• If you are pregnant and your doctor forbids you to take this medication stop taking
• You must inform your health care if you have any medical history or critical health issue

Ventoclax and Azacitidine

Doctors use ventoclax and azacitidine to treat a certain type of cancer, like leukemia. Ventoclax blocks a protein that helps cancer cells survive. On the other hand, azacitidine interferes with the production of DNA and RNA in cancer cells, which leads them to die.

Doctors sometimes use these drugs together, especially in older adults with leukemia who can’t have intensive chemotherapy. This combination has shown better results than using azarest alone. It offers hope for patients who are looking for alternative treatment.

Azarest-300mg(Azacitidine) Cost

The cost of azarest varies based on the brand, country, and health insurance. Azarest is a popular brand that often costs less than others.

If you’re interested in purchasing azarest, contact us via WhatsApp, WeChat, Telegram, or email. Just send your query, the amount you need, and your prescription details. We’re here to help!

Azarest-300mg(Azacitidine) Side Effects

Like any other medication azarest can cause side effects. Common side effects of azarest include:

• Low blood cell counts Increases infection and bleeding risks.
• Gastrointestinal issues: Nausea, vomiting, diarrhea, constipation, manageable with meds and diet.
• Fatigue: Common with cancer treatments.
• Injection site reactions: Redness, pain, bruising.
• Other: Headache, muscle/joint pain, appetite loss, hair loss.

Serious side effects may include:

• Tumor lysis syndrome: Rare but severe complication.
• Liver problems: Monitored with blood tests.
• Heart problems: Irregular heartbeat, chest pain (rare).
• Infection risk: Due to a weakened immune system.

Azarest (Azacitidine) Success Rate

Success depends on the condition and goal:

1. Complete remission (CR): No signs of the disease.
2. Overall response rate (ORR): Includes CR, partial remission (PR), and improved blood counts.
3. Overall survival (OS): How long a patient lives after treatment.

Success rates differ by condition:

1. MDS: Improves blood counts, reduces transfusions, and extends survival. ORR: 20-70%, OS: 12-37 months.
2. AML: Used in older or unfit patients. ORR: 20%, OS: 7-24 months.
3. CMML: Enhances blood counts and delays AML. ORR: 20-30%, OS: 12-24 months.

Factors affecting success:

1. Disease type and severity.
2. Patient’s age and health.
3. Prior treatments.
4. Treatment regimen: Dose, schedule, and combination with other drugs.

A Few Factors You Should Know about Azacitidine

• It is available in two forms oral azarest and azarest injection
• Azacitidine chemo care: It is a chemotherapy medication used to treat MDS, AML, and CMML.
• Everest pharmaceutical is the azarest-300mg(azacitidine) manufacturer.

FAQs about Azacitidine

Q-1: Can azacitidine cure MDS(myelodysplastic syndromes )?

A: It doesn’t usually cure MDS, but it can help improve blood counts, reduce transfusions, and delay disease progression.

Q-2: How does azarest-(azacitidine) work?

A: Azarest works by interfering with the DNA in cancer cells, ultimately causing them to die off.

Q-3: How is azacitidine administered?

A: As it is available in both oral and injection form, doctors can administer it in both ways.

Q-4: Is azarest-(azacitidine) chemotherapy or immunotherapy?

A: Yes, now health care professionals using this medication as an alternative to chemotherapy in many cases. Where it hinders DNA & RNA in cancer cells.

Q-5: How many cycles of azacitidine and ventoclax?

A: Azacitidine and venetoclax cycles vary for each person. Talk to your doctor about your specific condition, goals, and health to determine the best treatment plan for you. They’ll monitor your progress and adjust the cycles as needed. Don’t try to manage your treatment alone!

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