304 North Cardinal St.
Dorchester Center, MA 02124
Product name: Abiret
Generic Name: Abiraterone Acetate
Brand Name: ZYTIGA
Volume: 120 tablets
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Abiret-250mg-Abiraterone Acetate is a medication used in the treatment of advanced prostate cancer. It belongs to a class of drugs called androgen biosynthesis inhibitors.Abiret-250mg acetate works by inhibiting an enzyme called CYP17, which is involved in the production of androgens (male hormones) such as testosterone.
Abiret-250mg is usually prescribed in combination with another medication called prednisone or prednisolone, which helps to manage side effects and maximize the effectiveness of the treatment. This combination therapy is commonly used in patients with metastatic castration-resistant prostate cancer (mCRPC), where the cancer has spread to other parts of the body and is no longer responsive to hormone therapy. 1
Abiraterone is used for treating metastatic castration-resistant prostate cancer (mCRPC) in combination with methylprednisolone or prednisone. It is also used in Europe and Canada for patients who are asymptomatic or mildly symptomatic after androgen deprivation therapy failure and for those who have received prior chemotherapy containing docetaxel after the failure of androgen deprivation therapy. In Europe and Canada, it may be used in combination with prednisolone and androgen deprivation therapy in newly diagnosed patients. In Canada and the US, abiraterone is available in a combination product with niraparib for adults with BRCA-mutated mCRPC.
Abiret-250mg is a medication used to treat metastatic castration-resistant prostate cancer (mCRPC) in combination with methylprednisolone 9 or prednisone. It is also used in Europe and Canada for patients who are asymptomatic or mildly symptomatic after the failure of androgen deprivation therapy and for those who have received prior chemotherapy containing docetaxel after the failure of androgen deprivation therapy. In Europe, it is used for patients whose disease has progressed on or after a docetaxel-based chemotherapy regimen. It is used for patients in Canada who have received prior chemotherapy containing docetaxel after the failure of androgen deprivation therapy. In Canada and the US, abiraterone is also available in a combination product with niraparib for adults with deleterious or suspected deleterious BRCA-mutated mCRPC.
Metastatic high-risk castration-sensitive prostate cancer (CSPC) in combination with prednisone. This is a type of prostate cancer that is still sensitive to castration therapy, but has a high risk of spreading to other parts of the body. 2
Abiret-250mg is a CYP17A1 inhibitor, which means that it blocks the production of testosterone and other androgens in the body. Androgens are hormones that can fuel the growth of prostate cancer cells. By blocking androgen production, Abiret-250mg can help slow or stop the growth of prostate cancer.
CYP17A1 is a key enzyme in the androgen biosynthesis pathway. It catalyzes two important steps in the pathway:
DHEA and androstenedione are converted to testosterone in the testes and adrenal glands. Testosterone is the main androgen hormone in the body, and it is essential for the growth and development of prostate cancer cells.
Abiret-250mg works by reversibly inhibiting CYP17A1. This blocks the production of DHEA and androstenedione and consequently reduces the amount of testosterone in the body. 3
Dosage: Abiret-250mg is typically available in tablet form, and the recommended dose is usually 1,000 mg (four 250 mg tablets) taken once daily. However, the exact dosage may differ based on individual patient factors, such as overall health, tolerability, and other medications being used.
Administration: Abiret-250mg should be taken on an empty stomach, at least one hour before or two hours after a meal. Taking it with food can significantly reduce the absorption and effectiveness of the medication. The tablets should be swallowed whole with water, and it is important not to crush, chew, or break them.
Monitoring: During treatment with Abiret-250mg, regular monitoring and follow-up visits with the healthcare provider are important. This may include blood tests to assess liver function, blood pressure, and other relevant parameters. The healthcare team will determine the frequency of these tests based on individual patient needs.
Concomitant Medication: Abiret-250mg is typically prescribed in combination with a low-dose corticosteroid, such as prednisone or prednisolone. The corticosteroid helps to manage side effects and optimize the effectiveness of abiraterone acetate. The specific dosage and administration of the corticosteroid will be determined by the healthcare provider. 4
Abiret-250mg can cause various side effects, including fatigue, hot flashes, high blood pressure, joint pain, muscle pain, diarrhea, nausea, vomiting, weight loss, cough, headache, constipation, and difficulty sleeping. Less common side effects include liver problems, heart problems, bone fractures, low potassium levels, high blood sugar, anemia, rash, skin darkening, depression, anxiety, confusion, and seizures. It’s crucial to inform your doctor about all medications.
The price of abiraterone acetate (Zytiga®) can vary depending on a number of factors, including the dosage, the pharmacy where you purchase it, and whether or not you have insurance.
According to GoodRx, the average retail price for a 30-day supply of abiraterone acetate 250 mg is $13,715. However, with a GoodRx discount, you can pay as little as $2,755.
But the price of Abiret-250mg is very less than that. to know price contact us.
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